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Article

Differential roles of Angiotensinogen and Angiotensin Receptor type 1 polymorphisms in breast cancer risk.

Breast cancer research and treatment - 1 Mar 2007

González-Zuloeta Ladd A M, Arias Vásquez A, Siemes C, Yazdanpanah M, Coebergh J W, Hofman A, Stricker B H Ch, van Duijn C M

Abstract excerpt

While angiotensinogen (AGT) seems to have anti proliferative properties, angiotensin II (ATII) is a potent growth factor and it mediates its actions through the angiotensin type 1 receptor (AGTR1). In the AGT gene, the M235T polymorphism has been associated with the variation in angiotensinogen levels and in the AGTR1 gene; the C573T variant is associated with different pathologies. We aimed to evaluate the...

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Source

Identifiers

PMID: 16823505
DOI: 10.1007/s10549-006-9290-0

Genes

AGT
AGTR1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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