A genetic basis for anomalous band patterns encountered during DNA STR profiling.

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Article

A genetic basis for anomalous band patterns encountered during DNA STR profiling.

Journal of forensic sciences - 1 Nov 2004

Clayton Tim M, Guest Jennifer L, Urquhart Andy J, Gill Peter D

Abstract excerpt

Since 1995 the Forensic Science Service (FSS) has carried out DNA profiling of reference samples for the UK National DNA Database and in forensic casework using two multiplex STR profiling systems. During this period, profiles with anomalous banding patterns, although comparatively rare, have been encountered regularly. The FSS has collected instances of triallelic patterns and aberrant diallelic patterns. A...

Topics

Child
Chromosome Banding
DNA Fingerprinting
DNA Mutational Analysis
Female
Gene Rearrangement
Genetic Variation
Humans
Loss of Heterozygosity
Male
Tandem Repeat Sequences

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Open in PubMed

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PMID: 15568691

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