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Molecular cloning and characterization of a large subunit of Salmonella typhimurium glutamate synthase (GOGAT) gene in Escherichia coli.

Journal of microbiology (Seoul, Korea) - 1 Jun 2006

Chung Tae-Wook, Lee Dong-Ick, Kim Dong-Soo, Jin Un-Ho, Park Chun, Kim Jong-Guk, Kim Min-Gon, Ha Sang-Do, Kim Keun-Sung, Lee Kyu-Ho, Kim Kwang-Yup, Chung Duck Hwa, Kim Cheorl-Ho

Abstract excerpt

Two pathways of ammonium assimilation and glutamate biosynthesis have been identified in microorganisms. One pathway involves the NADP-linked glutamate dehydrogenase, which catalyzes the amination of 2-oxoglutarate to form glutamate. An alternative pathway involves the combined activities of glutamine synthetase, which aminates glutamate to form glutamine, and glutamate synthase, which transfers the amide group...

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PMID: 16820760

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