Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic features of the X chromosome affect pubertal development and testicular degeneration in adolescent boys with Klinefelter syndrome.

Clinical endocrinology - 1 Jul 2006

Wikström Anne M, Painter Jodie N, Raivio Taneli, Aittomäki Kristiina, Dunkel Leo

Abstract excerpt

OBJECTIVE: To investigate how genetic features of the X chromosome influence growth, pubertal development and testicular degeneration in adolescent boys with Klinefelter syndrome (KS). Previous studies have suggested that genetic features of the X chromosome may contribute to the wide phenotypic variation in KS. DESIGN: A prospective clinical study. PATIENTS: Fourteen nonmosaic 47,XXY boys, aged 10-13.9 years....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomes, Human, X
Share to Dosage Compensation, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Klinefelter Syndrome

Share to Puberty

Share to Receptors, Androgen

Share to Testis

Share to Trinucleotide Repeats

Share to X Chromosome Inactivation

Source

Identifiers

PMID: 16817826
DOI: 10.1111/j.1365-2265.2006.02554.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic features of the X chromosome affect pubertal development and testicular degeneration in adolescent boys with Klinefelter syndrome.PMID 16817826Read ↗

Androgen receptor CAGn repeat length influences phenotype of 47,XXY (Klinefelter) syndrome.Semantic proximity Read ↗

Effect of ascertainment and genetic features on the phenotype of Klinefelter syndrome.Semantic proximity Read ↗

Gonadal dysfunction and beyond: Clinical challenges in children, adolescents, and adults with 47,<scp>XXY</scp> Klinefelter syndromeSemantic proximity Read ↗

Klinefelter Syndrome in Childhood: Variability in Clinical and Molecular FindingsSemantic proximity Read ↗

From Klinefelter Syndrome to High Grade Aneuploidies: Expanding the Gene-dosage Effect of Supernumerary X ChromosomesSemantic proximity Read ↗

New Horizons in Klinefelter Syndrome: Current Evidence, Gaps, and Research PrioritiesSemantic proximity Read ↗

Genotype and phenotype in Klinefelter syndrome - impact of androgen receptor polymorphism and skewed X inactivation.Semantic proximity Read ↗

Chromosomal Variants in Klinefelter SyndromeSemantic proximity Read ↗

Novel genetic aspects of Klinefelter's syndrome.Semantic proximity Read ↗

New approaches to the Klinefelter syndrome.Semantic proximity Read ↗

The Klinefelter syndrome is associated with high recurrence of copy number variations on the X chromosome with a potential role in the clinical phenotype.Semantic proximity Read ↗

Immunoexpression of Androgen Receptor and Nine Markers of Maturation in the Testes of Adolescent Boys with Klinefelter Syndrome: Evidence for Degeneration of Germ Cells at the Onset of MeiosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.