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Article

Association of lipoprotein lipase S447X, apolipoprotein E exon 4, and apoC3 -455T>C polymorphisms on the susceptibility to diabetic nephropathy.

Clinical genetics - 1 Jul 2006

Ng M C Y, Baum L, So W-Y, Lam V K L, Wang Y, Poon E, Tomlinson B, Cheng S, Lindpaintner K, Chan J C N

Abstract excerpt

Diabetic nephropathy (DN) is the leading cause of end-stage renal disease. In DN patients, triglyceride (TG) level is elevated and lipoprotein lipase (LPL) activity, which hydrolyzes TG, is decreased. The LPL S447X and apolipoprotein E (APOE) exon 4 polymorphisms affect TG levels, and the APOC3 -455T>C polymorphism affects LPL activity. Our aim was to examine the association of these polymorphisms with...

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Source

Identifiers

PMID: 16813599
DOI: 10.1111/j.1399-0004.2006.00628.x

Genes

LPL
APOE
APOC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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