Article
[Immunophenotyping of epithelioid-cell granulomas in sarcoidosis].
Problemy tuberkuleza i boleznei legkikh - 1 Jan 2006
Guntupova L D, Borisov S E, Typitsyn N N, Solov'eva I P, Ots O N, Latyshev A N, Semenov G I
Abstract excerpt
The specimens of biopsy of the lung and lymph nodes from 24 patients with sarcoidosis were immunophenotyped. The monoclonal antibody panel for immunophenotyping the monocyte-macrophage cells included HLA-DR, CD64, CD163; CD7, CD3, CD4, CD8, HLA-DR, and CD20 were used to assess lymphocytic populations. In sarcoidosis, the majority of cell elements of a granuloma are in a state of activation, as evidenced by HLA-DR...
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