Article
Cytochrome P-450 2D6 and 2C19 polymorphisms and length of hospitalization in psychiatry.
Clinical laboratory - 1 Jan 2006
Kropp Stefan, Lichtinghagen Ralf, Winterstein Kathrin, Schlimme Jann, Schneider Udo
Abstract excerpt
We evaluated whether cytochrome P450 (CYP) poor metabolizer polymorphisms of CYP2D6 and CYP2C19 are relevant for the outcome (measured by length of hospitalization) during treatment with psychotropic medications in patients with depression or schizophrenia. 229 patients were genotyped by real-time PCR hybridization probe melting curve technique for CYP2C19*2, CYP2D6*3, *4, and *6, respectively. The gene deletion...
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