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Article

A new paradigm for West syndrome based on molecular and cell biology.

Epilepsy research - 1 Aug 2006

Kato Mitsuhiro

Abstract excerpt

Symptomatic West syndrome has heterogeneous backgrounds. Recently, two novel genes, ARX and CDKL5, have been found to be responsible for cryptogenic West syndrome or infantile spasms. Both are located in the human chromosome Xp22 region and are mainly expressed and play roles in fetal brain. Moreover, several genes responsible for brain malformations including lissencephaly, which is frequently associated with...

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Source

Identifiers

PMID: 16806828
DOI: 10.1016/j.eplepsyres.2006.02.008

Genes

ARX
CDKL5
DCX
MECP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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