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Article

Increased adhesive and inflammatory properties in blood outgrowth endothelial cells from sickle cell anemia patients.

Microvascular research - 1 Nov 2013

Sakamoto Tatiana Mary, Lanaro Carolina, Ozelo Margareth Castro, Garrido Vanessa Tonin, Olalla-Saad Sara Teresinha, Conran Nicola, Costa Fernando Ferreira

Abstract excerpt

The endothelium plays an important role in sickle cell anemia (SCA) pathophysiology, interacting with red cells, leukocytes and platelets during the vaso-occlusive process and undergoing activation and dysfunction as a result of intravascular hemolysis and chronic inflammation. Blood outgrowth endothelial cells (BOECs) can be isolated from adult peripheral blood and have been used in diverse studies, since they...

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Identifiers

PMID: 24144783
DOI: 10.1016/j.mvr.2013.10.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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