Article
LuxS involvement in the regulation of genes coding for hemin and iron acquisition systems in Porphyromonas gingivalis.
Infection and immunity - 1 Jul 2006
James Chloe E, Hasegawa Yoshiaki, Park Yoonsuk, Yeung Vincent, Tribble Gena D, Kuboniwa Masae, Demuth Donald R, Lamont Richard J
Abstract excerpt
The periodontal pathogen Porphyromonas gingivalis employs a variety of mechanisms for the uptake of hemin and inorganic iron. Previous work demonstrated that hemin uptake in P. gingivalis may be controlled by LuxS-mediated signaling. In the present study, the expression of genes involved in hemin and iron uptake was determined in parent and luxS mutant strains by quantitative real-time reverse transcription-PCR....
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