Article
Novel genes implicated in embryonal, alveolar, and pleomorphic rhabdomyosarcoma: a cytogenetic and molecular analysis of primary tumors.
Neoplasia (New York, N.Y.) - 1 May 2006
Goldstein Myriam, Meller Isaac, Issakov Josephine, Orr-Urtreger Avi
Abstract excerpt
Rhabdomyosarcoma, the most common pediatric soft tissue sarcoma, likely results from deregulation of the skeletal myogenesis program. Although associations between PAX3, PAX7, FOXO1A, and RMS tumorigenesis are well recognized, the entire spectrum of genetic factors underlying RMS development and...
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