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In Silico Identification of Potential Therapeutic Targets in the Human Pathogen Helicobacter Pylori

1 Jan 2006

Abstract excerpt

Availability of genome sequences of pathogens has provided a tremendous amount of information that can be useful in drug target and vaccine target identification. One of the recently adopted strategies is based on a subtractive genomics approach, in which the subtraction dataset between the host and pathogen genome provides information for a set of genes that are likely to be essential to the pathogen but absent...

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PMID: 16789912
DOI: 10.3233/isb-00220

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