Hyperinfectivity in Cholera: A New Mechanism for an Old Epidemiological Model?

Abstract excerpt

Hartley et al. [ 1] have recently proposed an epidemiological model for the dynamics of cholera that explicitly incorporates a hyperinfectious stage of the pathogen Vibrio cholerae, following laboratory findings that passage of the bacterium through the gastrointestinal tract results in a short-lived more highly infectious state. The paper and its commentary [ 2] emphasize that this model provides a basis for the...

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