Article
Altered beta-amyloid precursor protein isoforms in Mexican Alzheimer's Disease patients.
Disease markers - 1 Jan 2006
Sánchez-González V J, Ortiz G G, Gallegos-Arreola P, Macías-Islas M A, Arias-Merino E D, Loera-Castañeda V, Martínez-Cano E, Velázquez-Brizuela I E, Rosales-Corral S A, Curiel-Ortega C R, Pacheco-Moisés F, García J J
Abstract excerpt
OBJECTIVE: To determine the beta-amyloid precursor protein (betaAPP) isoforms ratio as a risk factor for Alzheimer's Disease and to assess its relationship with demographic and genetic variables of the disease. METHODS: Blood samples from 26 patients fulfilling NINCDS-ADRDA diagnostic criteria for AD and 46 healthy control subjects were collected for Western blotting for betaAPP. A ratio of betaAPP isoforms, in...
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