Article
Coupled expression of MhpE aldolase and MhpF dehydrogenase in Escherichia coli.
Biochemical and biophysical research communications - 4 Aug 2006
Lee Sang-Joon, Ko Jae-hyeong, Kang Han-Young, Lee Younghoon
Abstract excerpt
MhpE (4-hydroxy-2-ketovalerate aldolase) and MhpF [acetaldehyde dehydrogenase (acylating)] are responsible for the last two reactions in the 3-(3-hydroxyphenyl)propionate (3-HPP) catabolic pathway in Escherichia coli, which is homologous to the meta-cleavage pathway in Pseudomonas species. Here, we report that the MhpE aldolase is associated with the MhpF dehydrogenase and that MhpF is indispensable for the...
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