Article
Clustering of isochorismate synthase genes menF and entC and channeling of isochorismate in Escherichia coli.
Biochimica et biophysica acta - 30 Dec 2001
Buss K, Müller R, Dahm C, Gaitatzis N, Skrzypczak-Pietraszek E, Lohmann S, Gassen M, Leistner E
Abstract excerpt
There are two isochorismate synthase genes entC and menF in Escherichia coli. They encode enzymes (isochorismate synthase, EC 5.4.99.6) which reversibly synthesize isochorismic acid from chorismic acid. The genes share a 24.2% identity but are differently regulated. Activity of the MenF isochorismate synthase is significantly increased under anaerobic conditions whereas the activity of the EntC isochorismate...
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