Article
MEF2C mediates the activation induced cell death (AICD) of macrophages.
Cell research - 1 Jun 2006
Fu Wenxia, Wei Jinxue, Gu Jun
Abstract excerpt
Activation-induced cell death (AICD) of immune cells is widely believed to be crucial for the regulation of immune responses. Although macrophage apoptosis has been observed under a variety of pathological conditions, questions as to whether there is AICD of macrophages and how macrophage life span is regulated have not been well addressed. AICD in macrophages requires two signals. One is cell activation...
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