Article
Circumventing Resistance to Kinase-Inhibitor Therapy
14 Jun 2006
Abstract excerpt
Throughout its history, chronic myeloid leukemia (CML) has set precedents for cancer research and therapy, ranging from the identification of the first specific chromosomal abnormality associated with cancer to the development of imatinib as a specific, targeted therapy for the disease.1 In this issue of the Journal, two articles2,3 continue this tradition by describing how an understanding of resistance to...
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