Article
Influence of genomic loci on measures of chronic kidney disease in hypertensive sibships.
Journal of the American Society of Nephrology : JASN - 1 Jul 2006
Turner Stephen T, Kardia Sharon L R, Mosley Thomas H, Rule Andrew D, Boerwinkle Eric, de Andrade Mariza
Abstract excerpt
Genomewide linkage analyses were conducted of serum creatinine, estimated GFR (eGFR), and urine albumin-creatinine ratio (UACR) in search of genetic susceptibility loci for chronic kidney disease in 1351 black (median age 63 yr, 70% women, 79% hypertensive) and 1022 white individuals (median age 61 yr, 56% women, 75% hypertensive) from sibships in which two or more members had essential hypertension diagnosed...
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