Article
Genome scan of glomerular filtration rate and albuminuria: the HyperGEN study.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Mar 2007
Leon Joanlise M, Freedman Barry I, Miller Michael B, North Kari E, Hunt Steven C, Eckfeldt John H, Lewis Cora E, Kraja Aldi T, Djoussé Luc, Arnett Donna K
Abstract excerpt
BACKGROUND: Albuminuria and reduced glomerular filtration rate (GFR) are markers of renal dysfunction associated with hypertension. We performed genome-wide scans to detect loci impacting these parameters in 1251 African American (AAs) and 1129 European American (EAs) hypertensive siblings from the Hypertension Genetic Epidemiology Network study. METHODS: GFR, estimated by the Modification of Diet in Renal...
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