Article
Apoptosis: a potential role for cytosolic transglutaminase and its importance in tumour progression.
Biochimica et biophysica acta - 5 Jun 1991
Knight C R, Rees R C, Griffin M
Abstract excerpt
The relationship between transglutaminase activity, apoptosis and the propensity of a tumour to metastasise, was investigated in a series of metastatic variants of an HSV-2 induced hamster fibrosarcoma and two metastatic variants of the B16 mouse melanoma. The data suggest an inverse relationship...
Topics
- Animals
- Cell Membrane
- Cell Survival
- Chromatography, Ion Exchange
- Cricetinae
- Cytosol
- Fibrosarcoma
- Melanoma
- Mice
- Neoplasm Metastasis
- Phenotype
- Transglutaminases
- Tumor Cells, Cultured