Article
RFLP analysis with cDNA probes for DQ/DP region in HLA identical sibling marrow transplants: lack of correlation with GvHD.
Haematologica - 1 Jan 2000
Gaozza E, Piccoli P, Ferrara G B, Bacigalupo A
Abstract excerpt
BACKGROUND: The role of HLA-DP as transplantation antigen in contributing to GvHD is a matter of current debate. HLA-DP, is encoded centromeric to DR-DQ and its alleles are in weak linkage disequilibrium with the rest of the MHC; thus a certain number of HLA matched pairs could be actually DP incompatible to study a possible correlation between HLA-DP matching and GvHD, 24 HLA identical BMT/donor-recipient...
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