Article
Selection of unrelated bone marrow donors: does the current procedure warrant complete MHC class II identity?
Beitrage zur Infusionstherapie = Contributions to infusion therapy - 1 Jan 1992
Eiermann T H, Ballas M, Fakler J, Müller C, Wölpl A, Goldmann S F
Abstract excerpt
Bone marrow transplantation from unrelated donors is being used increasingly for the treatment of patients with leukemia and several other hematologic disorders. Selection of unrelated bone marrow donors currently relies on serological HLA identity and negative mixed lymphocyte reactions between donor/recipient pairs. As serological HLA-DP typing is not feasible, we used the HLA-DPB1 oligonucleotide typing method...
Topics
- Bone Marrow Transplantation
- Cytotoxicity Tests, Immunologic
- Genes, MHC Class II
- Histocompatibility Testing
- Humans
- Lymphocyte Culture Test, Mixed
- Phenotype
- Polymorphism, Genetic
- Tissue Donors
