Article
Sequence analysis of the genes encoding for H+/K+-ATPase in autoimmune gastritis.
Annals of medicine - 1 Jan 2006
Oksanen Aino M, Lemmelä Susanna M, Järvelä Irma E, Rautelin Hilpi I
Abstract excerpt
BACKGROUND: H+/K+-ATPase is the target autoantigen in autoimmune gastritis (AIG), an organ-specific autoimmune disease with a strong hereditary component. AIM: To detect possible polymorphisms in H+/K+-ATPase alpha- and beta-subunits in AIG patients. METHODS: Blood samples from 12 Finnish AIG patients were sequenced for the coding regions of genes encoding for H+/K+-ATPase alpha- and beta-subunits; 50-52 Finnish...
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