Gene Expression Profiling as a Window into Idiopathic Pulmonary Fibrosis Pathogenesis: Can We Identify the Right Target Genes?

Abstract excerpt

Expression microarrays that provide genome-level, transcriptional, high-resolution profiles have been applied successfully to multiple diseases. Although microarrays provide information regarding thousands of genes, many investigators prefer to focus on a single gene and validate its role, an approach often supported by grant and journal reviewers. Only a minority of investigators focus on global changes in gene...

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