Article
Adrenoceptor polymorphisms and the risk of cardiac injury and dysfunction after subarachnoid hemorrhage.
Stroke - 1 Jul 2006
Zaroff Jonathan G, Pawlikowska Ludmila, Miss Jacob C, Yarlagadda Sirisha, Ha Connie, Achrol Achal, Kwok Pui-Yan, McCulloch Charles E, Lawton Michael T, Ko Nerissa, Smith Wade, Young William L
Abstract excerpt
BACKGROUND AND PURPOSE: Cardiac abnormalities occur commonly after subarachnoid hemorrhage (SAH) and may be caused by excessive release of catecholamines from the myocardial sympathetic nerves. We hypothesized that adrenoceptor polymorphisms resulting in greater catecholamine sensitivity would be associated with an increased risk of cardiac injury. METHODS: This was a prospective cohort study. The primary outcome...
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