Article
Intrahost variations in the envelope receptor-binding domain (RBD) of HTLV-1 and STLV-1 primary isolates.
Retrovirology - 25 May 2006
Kim Felix J, Lavanya Madakasira, Gessain Antoine, Gallego Sandra, Battini Jean-Luc, Sitbon Marc, Courgnaud Valérie
Abstract excerpt
Four primate (PTLV), human (HTLV) and simian (STLV) T-cell leukemia virus types, have been characterized thus far, with evidence of a simian zoonotic origin for HTLV-1, HTLV-2 and HTLV-3 in Africa. The PTLV envelope glycoprotein surface component (SUgp46) comprises a receptor-binding domain (RBD) that alternates hypervariable and highly conserved sequences. To further delineate highly conserved motifs in PTLV...
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