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Article

Resistance to apoptosis‐inducing stimuli in CD44+ head and neck squamous cell carcinoma cells

5 Apr 2011

Abstract excerpt

BACKGROUND: CD44 was identified previously as a surface marker in cancer stem cells (CSCs) of head and neck squamous cell carcinoma (HNSCC). Most cancer treatments have been linked to the activation of the apoptosis-signaling pathway; however, the resistance mechanisms to apoptosis in CSCs have not yet been fully elucidated. METHODS: The sensitivity of CD44+ cells to diverse apoptosis-inducing stimuli was...

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PMID: 21472882
DOI: 10.1002/hed.21732

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