Article
Selective regimen shift and demographic growth increase associated with the emergence of high-fitness variants of canine parvovirus.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jun 2007
Pereira César A D, Leal Elcio S, Durigon Edison L
Abstract excerpt
The natural evolution of Canine parvovirus (CPV) is characterized by a variety of mutations, mainly in the VP1/VP2 gene. Although positive selection has been previously reported in CPV, little is known about its overall contribution to viral adaptation in the canine population. Herein, the influences of the evolutive constraints on CPV during a period of viral adaptation into a previously uninfected population...
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