Article
Microarray-based identification of antigenic variants of foot-and-mouth disease virus: a bioinformatics quality assessment.
BMC genomics - 18 May 2006
Martín Verónica, Perales Celia, Abia David, Ortíz Angel R, Domingo Esteban, Briones Carlos
Abstract excerpt
BACKGROUND: The evolution of viral quasispecies can influence viral pathogenesis and the response to antiviral treatments. Mutant clouds in infected organisms represent the first stage in the genetic and antigenic diversification of RNA viruses, such as foot and mouth disease virus (FMDV), an important animal pathogen. Antigenic variants of FMDV have been classically diagnosed by immunological or RT-PCR-based...
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