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Article

Long-duration sCJD with PRNP codon 129 methionine homozygosity and cerebral cortical plaques.

Neurology - 27 Jun 2006

Lo Raymond Yen-Yu, Shyu Woei Cherng, Li Hung

Abstract excerpt

The authors investigated a 40-year-old woman who presented with ataxia and dementia with little progression for over 40 months. The results of a CSF 14-3-3 protein and EEG study did not reveal major abnormalities. Brain MRI showed increased signal intensity over the occipital cortex in diffusion-weighted imaging. To our knowledge, this is the longest MM-type sporadic Creutzfeldt-Jakob disease case with cortical...

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Identifiers

PMID: 16707728
DOI: 10.1212/01.wnl.0000217913.37108.94

Genes

PRNP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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