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Article

Association study of the human FZD3 locus with schizophrenia.

Biological psychiatry - 1 Dec 2003

Yang Jianzhong, Si Tianmei, Ling Yansu, Ruan Yan, Han Yonghua, Wang Xiling, Zhang Hongyan, Kong Qingmei, Li Xueni, Liu Cui, Zhang Darong, Zhou Mo, Yu Yaqin, Liu Shuzeng, Shu Liang, Ma Dalong, Wei Jun, Zhang Dai

Abstract excerpt

The FZD3 protein is a transmembrane receptor for secreted Wnt glycoproteins involved in the Wnt signal transduction cascades. The alteration of Wnt signal transduction cascades has been thought to be involved in producing the cytoarchitectural defects observed in schizophrenia. Because the human FZD3 gene is mapped to chromosome 8p21, which is a potential region containing a gene for schizophrenia, it may play a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 14643098
DOI: 10.1016/s0006-3223(03)00291-9

Genes

FZD3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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