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Host Range Restriction and Pathogenicity in the Context of Influenza Pandemic

1 Jun 2006

Abstract excerpt

Influenza A viruses cause pandemics at random intervals. Pandemics are caused by viruses that contain a hemagglutinin (HA) surface glycoprotein to which human populations are immunologically naive. Such an HA can be introduced into the human population through reassortment between human and avian virus strains or through the direct transfer of an avian influenza virus to humans. The factors that determine the...

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PMID: 16707041
DOI: 10.3201/eid1206.051336

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