Article
High-resolution mapping of quantitative trait loci affecting increased life span in Drosophila melanogaster.
Genetics - 1 Jul 2006
Wilson Rhonda H, Morgan Theodore J, Mackay Trudy F C
Abstract excerpt
Limited life span and senescence are near-universal characteristics of eukaryotic organisms, controlled by many interacting quantitative trait loci (QTL) with individually small effects, whose expression is sensitive to the environment. Analyses of mutations in model organisms have shown that genes affecting stress resistance and metabolism affect life span across diverse taxa. However, there is considerable...
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