Article
A novel assay for viral microRNA function identifies a single nucleotide polymorphism that affects Drosha processing.
Journal of virology - 1 Jun 2006
Gottwein Eva, Cai Xuezhong, Cullen Bryan R
Abstract excerpt
MicroRNAs (miRNAs) are a class of approximately 22-nucleotide noncoding RNAs that inhibit the expression of specific target genes at the posttranscriptional level. Recently, 11 miRNAs encoded by the pathogenic human herpesvirus Kaposi's sarcoma-associated herpesvirus (KSHV) were cloned from latently infected cells. While the expression of these miRNAs has been confirmed by Northern analysis, their ability to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
