Article
Killer cell immunoglobulin-like receptor (KIR) genes in the Basque population: association study of KIR gene contents with type 1 diabetes mellitus.
Human immunology - 1 Jan 2000
Santin Izortze, de Nanclares Guiomar Pérez, Calvo Begoña, Gaafar Ayman, Castaño Luis, Bilbao Jose Ramon
Abstract excerpt
Killer cell immunoglobulin-like receptors (KIR) form a group of regulatory molecules that specifically recognize HLA class I molecules, modulating cytolytic activity of natural killer cells. The number of KIR genes can vary between individuals, significant allelic variations have been described, and KIR genes are organized in a complex and heterogeneous family. In the present study we have performed KIR genotype...
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