Article
Interleukin-10 or tumor necrosis factor-alpha polymorphisms and the natural course of hepatitis C virus infection in a hyperendemic area of Japan.
Cytokine - 1 Apr 2006
Kusumoto Kazunori, Uto Hirofumi, Hayashi Katsuhiro, Takahama Yuka, Nakao Hiroyuki, Suruki Robert, Stuver Sherri O, Ido Akio, Tsubouchi Hirohito
Abstract excerpt
We investigated the effects of polymorphisms in interleukin (IL)-10 and tumor necrosis factor (TNF)-alpha on the natural course of hepatitis C virus (HCV) infection in a community-based population in Japan. A total of 460 anti-HCV antibody seropositive individuals were classified into two groups, those who were positive or negative for HCV RNA. In HCV RNA-positive individuals with at least four annual alanine...
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