Article
Mild hyperhomocysteinemia and the common C677T polymorphism of methylene tetrahydrofolate reductase gene are not associated with the metabolic syndrome in Type 2 diabetes.
Journal of endocrinological investigation - 1 Mar 2006
Russo G T, Di Benedetto A, Alessi E, Ientile R, Antico A, Nicocia G, La Scala R, Di Cesare E, Raimondo G, Cucinotta D
Abstract excerpt
A moderate increase of total homocysteine (tHcy) plasma levels seems to increase cardiovascular disease (CVD) risk in Type 2 diabetic subjects, but its relationship with diabetes and insulin-resistance is still controversial. We examined whether mild hyperhomocysteinemia and its major genetic determinant would cluster with the metabolic syndrome (MS) in Type 2 diabetes. One hundred Type 2 diabetic subjects with...
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