Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Plasma total homocysteine levels and methylenetetrahydrofolate reductase gene polymorphism in patients with type 2 diabetes mellitus.

Pathophysiology of haemostasis and thrombosis - 1 Jan 2008

Soares Anna L, Fernandes Ana P, Cardoso Jarbas E, Sousa Marinez O, Lasmar Marcelo C, Novelli Bethânia A, Lages Geralda F, Dusse Luci M, Vieira Lauro M, Lwaleed Bashir A, Carvalho Maria G

Abstract excerpt

BACKGROUND: Thrombotic episodes account for approximately 80% of deaths in type 2 diabetic patients. Hyperhomocysteinaemia is a well recognized independent risk factor for atherosclerosis and thromboembolism. Increased homocysteine levels may occur due to a number of factors including inherited gene polymorphism of methylenetetrahydrofolate reductase (MTHFR) C677T. Here, we evaluate plas- ma total homocysteine...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brazil
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2

Share to Homocysteine

Share to Hyperhomocysteinemia

Share to Hypertension

Share to Methylenetetrahydrofolate Reductase (NADPH2)

Share to Polymorphism, Single Nucleotide

Source

Identifiers

PMID: 19996639
DOI: 10.1159/000252825

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Plasma total homocysteine levels and methylenetetrahydrofolate reductase gene polymorphism in patients with type 2 diabetes mellitus.PMID 19996639Read ↗

Correlates of total homocysteine plasma concentration in type 2 diabetes.Semantic proximity Read ↗

Reduced serum homocysteine levels in type 2 diabetes.Semantic proximity Read ↗

Circulating homocysteine levels in patients with type 2 diabetes mellitus.Semantic proximity Read ↗

Thermolabile methylenetetrahydrofolate reductase enzyme genotype is frequent in type 2 diabetic patients with normal fasting homocysteine levels.Semantic proximity Read ↗

Polymorphism of the methylenetetrahydrofolate reductase gene association with homocysteine and ischemic stroke in type 2 diabetes.Semantic proximity Read ↗

Evaluation of plasma homocysteine level according to the C677T and A1298C polymorphism of the enzyme MTHRF in type 2 diabetic adults.Semantic proximity Read ↗

Effect of metabolic control on homocysteine levels in type 2 diabetic patients: a 3-year follow-up.Semantic proximity Read ↗

Methylenetetrahydrofolate Reductase (MTHFR) (C677T and A1298C) Polymorphisms and Vascular Complications in Patients with Type 2 Diabetes.Semantic proximity Read ↗

Association Between Homocysteine Level and Methylenetetrahydrofolate Reductase Gene Polymorphisms in Type 2 Diabetes Accompanied by Dyslipidemia.Semantic proximity Read ↗

Prevalence of methylenetetrahydrofolate reductase C677T and A1298C polymorphisms in Taiwanese patients with Type 2 diabetic mellitus.Semantic proximity Read ↗

Methylenetetrahydrofolate reductase gene polymorphism, hyperhomocysteinemia and occlusive retinal vascular disease in type 2 diabetic and non-diabetic subjects.Semantic proximity Read ↗

Does the MTHFR C677T gene polymorphism indicate cardiovascular disease risk in type 2 diabetes mellitus patients?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.