Article
Set regulation in asexual and sexual Plasmodium parasites reveals a novel mechanism of stage‐specific expression
16 Mar 2006
Abstract excerpt
Transmission of the malaria parasite depends on specialized gamete precursors (gametocytes) that develop in the bloodstream of a vertebrate host. Gametocyte/gamete differentiation requires controlled patterns of gene expression and regulation not only of stage and gender-specific genes but also of genes associated with DNA replication and mitosis. Once taken up by mosquito, male gametocytes undergo three mitotic...
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