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Article

A tubule cell line established from transgenic mice harboring temperature-sensitive simian virus 40 large T-antigen gene.

Japanese journal of cancer research : Gann - 1 Dec 1991

Yanai N, Satoh T, Kyo S, Abe K, Suzuki M, Obinata M

Abstract excerpt

Immortalization of cell lines with specific functions is important for examination of organ-specific functions in vitro. We established a kidney tubule cell line (TKC2) exhibiting a specific physiological response to hormone from the primary culture of kidneys of adult transgenic mice harboring temperature-sensitive SV40 large T-antigen gene. TKC2 cells showed temperature-sensitive growth in culture and exhibited...

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Identifiers

PMID: 1663919
DOI: 10.1111/j.1349-7006.1991.tb01803.x
PMCID: PMC5918353

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Source receipt: pubmed, retrieved 7 Sept 2026.

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