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Article

Population-based study of the relationship between mutations in the hemochromatosis (HFE) gene and arthritis.

Journal of gastroenterology and hepatology - 1 Mar 2006

Sherrington Colin A, Knuiman Matthew W, Divitini Mark L, Bartholomew Helen C, Cullen Digby J, Olynyk John K

Abstract excerpt

BACKGROUND AND AIM: Mutations in the hemochromatosis (HFE) gene are carried by one in three individuals of British Isles descent and may result in increased iron stores. These increased iron stores could potentially induce or exacerbate diseases, such as arthritis, in which iron has a role in pathogenesis. Although arthritis is a well-known association of clinically overt hereditary hemochromatosis, controversy...

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Source

Identifiers

PMID: 16638105
DOI: 10.1111/j.1440-1746.2006.04062.x

Genes

HFE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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