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Article

Creation of tumorigenic human endometrial epithelial cells with intact chromosomes by introducing defined genetic elements.

Oncogene - 14 Sept 2006

Mizumoto Y, Kyo S, Ohno S, Hashimoto M, Nakamura M, Maida Y, Sakaguchi J, Takakura M, Inoue M, Kiyono T

Abstract excerpt

Several genetic mutations have been identified in human endometrial cancers, but the specific combinations of mutations required to form endometrial cancer cells remain unknown. In the present study, we established an in vitro model of endometrial carcinogenesis, in which defined genetic elements were introduced into endometrial epithelial cells to create transformed endometrial cells at different stages....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to PTEN Phosphohydrolase

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Identifiers

PMID: 16636665
DOI: 10.1038/sj.onc.1209575

Genes

PTEN

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