Article
Successful immortalization of endometrial glandular cells with normal structural and functional characteristics.
The American journal of pathology - 1 Dec 2003
Kyo Satoru, Nakamura Mitsuhiro, Kiyono Tohru, Maida Yoshiko, Kanaya Taro, Tanaka Masaaki, Yatabe Noriyuki, Inoue Masaki
Abstract excerpt
The human endometrium is a dynamic tissue, the proliferative activity of which dramatically changes throughout the menstrual cycle, with exquisite regulation by sex-steroid hormones. Primary endometrial epithelial cells fall into senescence within 2 weeks when cultured on plastic dishes, and more complete understanding of endometrial biology has been delayed because of, in part, a lack of an in vitro culture...
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