Article
GeneRecon--a coalescent based tool for fine-scale association mapping.
Bioinformatics (Oxford, England) - 15 Sept 2006
Mailund Thomas, Schierup Mikkel H, Pedersen Christian N S, Madsen Jesper N, Hein Jotun, Schauser Leif
Abstract excerpt
UNLABELLED: GeneRecon is a tool for fine-scale association mapping using a coalescence model. GeneRecon takes as input case-control data from phased or unphased SNP and microsatellite genotypes. The posterior distribution of disease locus position is obtained by Metropolis-Hastings sampling in the state space of genealogies. Input format, search strategy and the sampled statistics can be configured through the...
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