Article
CoaSim: a flexible environment for simulating genetic data under coalescent models.
BMC bioinformatics - 14 Oct 2005
Mailund Thomas, Schierup Mikkel H, Pedersen Christian N S, Mechlenborg Peter J M, Madsen Jesper N, Schauser Leif
Abstract excerpt
BACKGROUND: Coalescent simulations are playing a large role in interpreting large scale intra-specific sequence or polymorphism surveys and for planning and evaluating association studies. Coalescent simulations of data sets under different models can be compared to the actual data to test the importance of different evolutionary factors and thus get insight into these. RESULTS: We have created the CoaSim...
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