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Identifying Mycobacterium tuberculosis complex strain families using spoligotypes.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Nov 2006

Vitol Inna, Driscoll Jeffrey, Kreiswirth Barry, Kurepina Natalia, Bennett Kristin P

Abstract excerpt

We present a novel approach for analysis of Mycobacterium tuberculosis complex (MTC) strain genotyping data. Our work presents a first step in an ongoing project dedicated to the development of decision support tools for tuberculosis (TB) epidemiologists exploiting both genotyping and epidemiological data. We focus on spacer oligonucleotide typing (spoligotyping), a genotyping method based on analysis of a direct...

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PMID: 16632413
DOI: 10.1016/j.meegid.2006.03.003

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