Article
Severe hearing loss in Dlxl mutant mice.
Hearing research - 1 Apr 2006
Polley Daniel B, Cobos Inma, Merzenich Michael M, Rubenstein John L R
Abstract excerpt
The Dlx homeobox gene family participates in regulating middle and inner ear development. A significant role for Dlxl, in particular,has been demonstrated in the development of the middle ear ossicles, but the functional consequences of Dlx.l gene mutation on hearing thresholds has not been assessed. The present study characterizes auditory brainstem responses to click and tonal stimuli in a non-lethal variant of...
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