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Article

A mouse model with postnatal endolymphatic hydrops and hearing loss.

Hearing research - 1 Mar 2008

Megerian Cliff A, Semaan Maroun T, Aftab Saba, Kisley Lauren B, Zheng Qing Yin, Pawlowski Karen S, Wright Charles G, Alagramam Kumar N

Abstract excerpt

Endolymphatic hydrops (ELH), hearing loss and neuronal degeneration occur together in a variety of clinically significant disorders, including Meniere's disease (MD). However, the sequence of these pathological changes and their relationship to each other are not well understood. In this regard, an animal model that spontaneously develops these features postnatally would be useful for research purposes. A search...

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PMID: 18289812
DOI: 10.1016/j.heares.2008.01.002
PMCID: PMC2858221

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