Article
NCI-H716 cells as a model for endocrine differentiation in colorectal cancer.
Virchows Archiv. B, Cell pathology including molecular pathology - 1 Jan 1992
de Bruïne A P, Dinjens W N, Pijls M M, vd Linden E P, Rousch M J, Moerkerk P T, de Goeij A F, Bosman F T
Abstract excerpt
In colonic neoplasms, endocrine differentiation is encountered not only in carcinoid tumors but also in adenocarcinomas, where endocrine cells may represent a distinct line of differentiation in the tumor. The significance of endocrine differentiation in colorectal cancer is not well established, partly because of the paucity of tumor cell lines which can serve as a model for studying endocrine differentiation....
Topics
- Animals
- Blotting, Northern
- Cecal Neoplasms
- Cell Differentiation
- Colorectal Neoplasms
- DNA
- Endocrine Glands
- Flow Cytometry
- Genotype
- Karyotyping
- Mice